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M Brothers Restaurant - By the Medure Brothers - M Brothers at Mayo, Jacksonville, FL

M Brothers at Mayo

4.8
4.8
461 Reviews
$50 and over
Seafood

Make a booking

2 people
7:00 pm
Booked 3 times today
  • Good for business meals
  • Good for special occasions
  • Fancy
Located inside Jacksonville's Mayo Clinic, M Brothers is the newest venture by the Medure Brothers, Chef Matthew and David Medure. Our menu has a focus on fresh seafood with an Asian and Mediterranean flair. Visit our lounge for a craft cocktail or select a bottle of wine from our extensive list. Serving Lunch and Dinner Monday - Saturday.

Dining areas

Additional information

  • Dining style
    Fine Dining
  • Price
    $50 and over
  • Cuisines
    Seafood, Asian, Mediterranean
  • Hours of Operation
    Lunch Mon–Fri 11:00 am–2:00 pm Dinner Mon–Sat 5:00 pm–9:00 pm
  • Phone number
    (904) 953-0409
  • Dress code
    Casual Dress

What 461 people are saying

Overall ratings and reviews

Reviews can only be made by diners who have eaten at this restaurant

4.8
4.8 based on recent ratings
  • 4.8Food
  • 4.8Service
  • 4.7Ambience
  • 4.5Value

NoiseModerate

Loved For

  • Jacksonville / Northeast Florida

    Innovative

  • Jacksonville

    Best Overall

  • Jacksonville

    Best Food

  • Jacksonville

    Innovative

Review summary

AI-generated from verified diner reviews
M Brothers at Mayo offers an exceptional dining experience with "innovative, fresh" dishes and "excellent" service. The restaurant's ambiance, located in the Mayo Clinic, is both "lovely" and "relaxing." Diners rave about the "fantastic" meals, including monthly special dinners and wine pairings. It's a "hidden gem" worth discovering.

461 Reviews
  1. Chris

    VIP

    Jacksonville

    54 reviews

    5.0

    54 reviews

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 3
    4. Ambience 5
    everything was great last night--food was excellent and drinks were wonderful only problem was the server was sniffling and coughing and sneezing from the first time she came to wait on us so that was an issue that needs corrected
    M Brothers at MayoResponded 3 days ago
    Thank you for your feedback and for dining with us. We're glad you enjoyed the food and drinks! We sincerely apologize for the issue with the server and will address it to ensure a better experience in the future.

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  2. Anne

    VIP

    Chicago

    8 reviews

    5.0

    8 reviews

    Dined 5 days ago

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    It was a treat to have a nice lunch (with wine!) during a day of medical appointments. Food was delicious and Douglas was a terrific server. We’ll be back!
    M Brothers at MayoResponded 3 days ago
    Thank you for joining us for lunch! We're delighted you enjoyed the food (and wine!) and appreciated Douglas's terrific service. We look forward to seeing you again soon!

    Is this helpful?

  3. Mary

    VIP

    New York City

    47 reviews

    5.0

    47 reviews

    Dined on 21 December 2024

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Fabulous dinner. Service was excellent We did the Japan dinner with wine pairings. Looking forward to the next one.
    M Brothers at MayoResponded 6 days ago
    Thank you for joining us for the Japan dinner! We’re thrilled you enjoyed the fabulous meal and wine pairings. Can’t wait to see you at the next one! 🍷🍣

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  4. Julie

    VIP

    Jacksonville

    14 reviews

    5.0

    14 reviews

    Dined on 18 December 2024

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 4
    Can I tell you how happy I am to get a Medure/Matthew's quality meal without having to suffer through the PV or downtown traffic? Douglas, our server, was so friendly and personable. It took a moment to adjust to eating a fine meal in a hospital, but it really was fantastic. We had the calamari, French onion soup, tonight's sea bass special, and the filet. All fantastic!!! Highly recommend!
    M Brothers at MayoResponded 6 days ago
    Thank you for the wonderful review! We're thrilled you enjoyed a Medure/Matthew's quality meal without the traffic. Douglas will be so pleased to hear your kind words! It’s great to know the atmosphere grew on you and that each dish exceeded expectations. We truly appreciate the recommendation and hope to see you again soon! 🍴✨

    1 person found this helpful

  5. Laurie

    Jacksonville

    1 review

    5.0

    1 review

    Dined on 9 December 2024

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Many people stopped by to say hello. They knew us and were friendly. Our server, Jordan, went above and beyond to care for us.
    M Brothers at MayoResponded on 12 December 2024
    Thank you for your kind words! We're thrilled to hear that Jordan and our team made you feel so welcome. We look forward to hosting you again soon! 😊🍴

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  6. GEORGE

    Charleston

    10 reviews

    2.0

    10 reviews

    Dined on 3 December 2024

    1. Overall 2
    2. Food 2
    3. Service 4
    4. Ambience 2
    I Had lunch numerous time there and was very happy first time dinner there the food was over cooked and dry mostly fried calamari French onion soup and triple tail fish of the day Very cafeteria style taste and donneness Very disappointed
    M Brothers at MayoResponded on 12 December 2024
    We're sorry to hear about your dinner experience and appreciate your feedback. This isn’t the standard we strive for, and we’ll address it with our team. We hope you’ll give us another chance to impress you.

    Is this helpful?

  7. Ellwood

    VIP

    New York City

    14 reviews

    5.0

    14 reviews

    Dined on 23 November 2024

    1. Overall 5
    2. Food 4
    3. Service 5
    4. Ambience 4
    The monthly food/wine tastings are exceptional. We never miss them. Morocco cuisine is just not my favorite. While the preparation and quality is excellent, I have never been a big fan of the spices particular to the area. The saxophonist played well, but it was a little loud.
    M Brothers at MayoResponded on 12 December 2024
    Thank you for your loyalty to our tastings! We’re glad you enjoyed the quality and preparation. We’ll pass along your feedback about the volume and look forward to welcoming you back for another exceptional evening! 🍷✨

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  8. Helen

    London

    37 reviews

    5.0

    37 reviews

    Dined on 21 November 2024

    1. Overall 5
    2. Food 5
    3. Service 5
    4. Ambience 5
    Dining at M Brothers is consistently great! Food is always delicious and perfectly prepared. The menu is filled with things we enjoy eating. And it is all served and delivered by your delightful team. Destiny is a worthy and engaging ambassador. I always look forward to seeing her. Makes the experience that much more special. M Brothers is a true gem.
    M Brothers at MayoResponded on 12 December 2024
    Thank you for your heartfelt review and kind words about Destiny! We're thrilled to hear she has such a positive impact on your visits and makes your experience extra special. We'll be sure to share your feedback with her and the team. It means the world to us to be a comforting part of your journey. 💙🍴

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  9. Margaret

    VIP

    Calgary

    3 reviews

    5.0

    3 reviews

    Dined on 20 November 2024

    1. Overall 5
    2. Food 5
    3. Service 3
    4. Ambience 4
    Wonderful food!! So convenient to have an outstanding and high quality restaurant at Mayo.
    M Brothers at MayoResponded on 12 December 2024
    Thank you for your kind words! We're delighted to provide a convenient and high-quality dining experience at M Brothers at Mayo. We look forward to serving you again soon! 😊🍴

    Is this helpful?

  10. Cristina

    Jacksonville

    1 review

    4.0

    1 review

    Dined on 19 November 2024

    1. Overall 4
    2. Food 5
    3. Service 4
    4. Ambience 3
    Risotto special was amazing !!!! Service was great. Amazing homemade bread
    M Brothers at MayoResponded on 12 December 2024
    Thank you for the glowing review! We're thrilled you loved the risotto special and our homemade bread. Looking forward to welcoming you back soon! 🍞✨🍽️

    Is this helpful?

FAQs

M Brothers at Mayo is rated 4.8 stars by 461 OpenTable diners.

Yes, you can generally book this restaurant by choosing the date, time and party size on OpenTable.

Make a booking

2 people
7:00 pm
Booked 3 times today
Google Map for M Brothers at Mayo

14335 Hospital Drive Suite 100, Jacksonville, FL 32224

Dining areas

Additional information

  • Cross Street
    San Pablo to W. Davis. Turn into Garage and look for complimentary VALET.
  • Area
    Jacksonville
  • Hours of Operation
    Lunch Mon–Fri 11:00 am–2:00 pm Dinner Mon–Sat 5:00 pm–9:00 pm
  • Price
    $50 and over
  • Cuisines
    Seafood, Asian, Mediterranean
  • Dining style
    Fine Dining
  • Dress code
    Casual Dress
  • Parking details
    Valet
  • Additional
    Bar/Lounge, Chef's Table, Non-Smoking, Private Room
  • Privacy policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
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