Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Southwest American Restaurants in South San Antonio

Price
Regions
Areas
Top Rated
Dining Options
Seating Options
Accessibility

58 restaurants available nearby

A photo of Chart House Restaurant - Tower of the Americas restaurant
4.5
Awesome(16489)
Price: Moderate
• Mexican • Downtown
Booked 144 times today
Dine in the heart of Downtown San Antonio at Chart House Restaurant, a haven of American cuisine that promises more than just a meal. Celebrated for both its culinary prowess and enchanting views, Chart House offers an array of finely-crafted American dishes, from fresh fish specialties to the sumptuous slow-roasted prime rib. Guests rave about the "delicious food and great service," with highlights including the "best key lime pie ever" and an original Hot Chocolate Lava Cake that perfectly concludes a memorable dining experience. Whether it's the stunning city vistas or the "exceptional service," Chart House provides a dining experience that consistently delights and surprises, making it a must-visit for locals and tourists alike.
A photo of Domingo Restaurante restaurant
4.5
Awesome(759)
Price: Expensive
• Mexican • Downtown
Booked 74 times today
Join us in our open-air restaurant on the Historic San Antonio River Walk with a natural ambiance where curated contemporary art intersects with a historical setting. Domingo's menus offer the flavors of South Texas and an agave-forward beverage program celebrating the culture of San Antonio with modern culinary flair.
A photo of Bohanan's Prime Steaks and Seafood restaurant
4.8
Exceptional(8220)
Price: Very Expensive
• Mexican • Downtown
Booked 61 times today
Bohanan's Prime Steaks and Seafood in downtown San Antonio is a gastronomic landmark where the allure of tender, prime beef and fresh seafood create a perfect dining experience. Known for its mesquite-grilled steaks like the "spectacular" Akaushi beef, Bohanan’s also boasts a AAA Four Diamond rating and a Wine Spectator’s Best of Award of Excellence. Diners rave about the "perfect steak doneness" and "spectacular table-side desserts flambé." The ambiance, set in a historic building near the River Walk, adds to its charm, making every visit memorable. It’s no wonder guests say, "Bohanan’s is consistently the best service in the city," making it a must-visit for anyone seeking the quintessential steakhouse experience.
A photo of Bliss Restaurant restaurant
4.9
Exceptional(4968)
Price: Very Expensive
• Mexican • Downtown
Booked 23 times today
Bliss is consistently among San Antonio’s best restaurants in terms of quality, service and atmosphere. Bliss is located just blocks away from downtown San Antonio in the burgeoning Southtown area. Our mission is to express excellence in the most inclusive, genuine and hospitable way. Bliss serves contemporary American cuisine. Our menu changes frequently with an emphasis on what is seasonal and creative over what is predictable and familiar. Our goal is to create a relaxed yet elegant dining experience in a genuine and comfortable environment.
A photo of Little Em's Oyster Bar restaurant
4.6
Exceptional(840)
Price: Expensive
• Mexican • Downtown
Booked 17 times today
Step into the charming world of Little Em's Oyster Bar, a celebrated seafood sanctuary nestled in the heart of Downtown San Antonio. This quaint eatery is renowned for its superb selection of oysters, sourced predominantly from Prince Edward Island, and praised for their "absolutely delicious and perfectly shucked" quality. Patrons rave about the fresh, buttery oysters and the beautifully crafted lobster rolls, consistently highlighting the "high quality" and "amazing" food. The atmosphere is as delightful as the menu, with a cozy setting that invites diners to indulge in a culinary journey underscored by exceptional service and a thoughtfully curated wine list. Whether you're a seafood aficionado or new to the delights of ocean fare, Little Em's promises a dining experience that's not just a meal, but a celebration of the sea's rich bounty.
A photo of Brenner's on the River Walk restaurant
4.7
Exceptional(278)
Price: Moderate
• Mexican • Downtown
Booked 31 times today
Brenner's on the River Walk in downtown San Antonio offers a quintessential American dining experience, combining tradition and elegance with a stunning three-story dining room overlooking the river. A continuation of the Brenner's legacy since 1936, this restaurant excels in crafting classic American dishes, especially its steaks which are often described as "cooked to perfection" and are a highlight among diners. Reviewers rave about the "amazing food amazing atmosphere" and the personalized service that makes each visit memorable. One guest mentioned, "The steak was flavorful and cooked to perfection," underscoring the restaurant's commitment to quality. Whether it's for a casual dinner or a special occasion, Brenner’s on the River Walk is celebrated for its exceptional American cuisine and vibrant ambiance, making it a must-visit culinary destination in San Antonio.
A photo of Supper restaurant
4.6
Exceptional(3149)
Price: Expensive
• Mexican • Downtown
Booked 36 times today
Supper, nestled in the heart of Downtown San Antonio, offers an exceptional Contemporary American dining experience that embodies the essence of South Texas hospitality. Housed in the historic and charming Hotel Emma, Supper is celebrated for its "phenomenal food service and ambiance." Diners rave about the "inventive seasonal cocktails" and the meticulously crafted dishes such as the "country fried quail" and "mushroom risotto," which are consistently lauded as "out of this world." The restaurant's commitment to quality is evident, with one guest noting, "the food and service were beyond phenomenal!" Whether it's a special occasion or a casual meal, Supper's vibrant atmosphere and culinary excellence make it a standout destination for Contemporary American cuisine.
A photo of Southerleigh Fine Food & Brewery restaurant
4.8
Exceptional(3079)
Price: Moderate
• Mexican • Downtown
Booked 40 times today
Southerleigh Fine Food & Brewery in downtown San Antonio masterfully celebrates Southern cuisine with a modern twist. Helmed by Chef Jeff Balfour, whose Galveston roots shine through in dishes like the "BEST shrimp boil entree in town!" and the mouth-watering crab mac and cheese, which has been called "the bomb." Diners rave about the "excellent service" and "fun environment," with specialties such as the jalapeño cornbread and crispy, juicy fried chicken consistently earning high praise. Located in the historic Pearl brewhouse, Southerleigh not only offers a delectable menu but also brews its own beer, providing a uniquely Southern experience that is both innovative and deeply rooted in tradition.
A photo of Blush Restaurant restaurant
4.7
Exceptional(64)
Price: Expensive
• Mexican • Downtown
Booked 11 times today
Blush Restaurant in Downtown San Antonio is renowned for its exceptional Bottle Service, elevating the dining experience with a touch of luxury and exclusivity. Patrons rave about the "foodgasmic flavors" and the "creative brunch menu," complemented by an innovative cocktail selection that enhances every meal. One visitor highlighted, "I had a special request of an Espresso Martini made with tequila reposado, the bartenders pulled it off for my palate!" The combination of skilled mixologists and attentive service, including "knowledgeable and sweet" staff like Matthew, ensures that each visit is memorable. Blush's Bottle Service is not just about drinks; it's about crafting unforgettable moments with every pour.
A photo of Mezquite restaurant
4.5
Awesome(186)
Price: Moderate
• Mexican • Downtown
Booked 30 times today
Nestled in the heart of Downtown San Antonio, Mezquite is a culinary gem that brings the vibrant flavors of the Sonoran region to life. Diners rave about the authenticity and quality of the cuisine, with one guest exclaiming, "The food and everything was beyond great!! Can’t wait to come back! Congratulations!" From the grilled meats and house-made flour tortillas to the exquisite cocktails, each dish is a celebration of tradition with a modern twist. The ambiance, whether on mariachi nights or a regular evening, enhances the dining experience, making every visit memorable. Whether it's the "life-changing" Elotes or the "divine" Carne Asada quesadilla, Mezquite stands out as a top destination for Mexican/Southwestern cuisine in San Antonio.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Privacy policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable Australia Level 22, 357 Collins Street, Melbourne, Victoria - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo