Enable JavaScript to run this app.
Skip to main content
OpenTable logo
  1. Home
  2. United States
  3. San Antonio

Best Fine Dining Restaurants in Medical Center

Price
Cuisine
Regions
Areas
Top Rated
Dining Options
Seating Options
Accessibility

26 restaurants available nearby

A photo of Dean's Steak & Seafood restaurant
4.6
Exceptional(200)
Price: Very Expensive
• Steak • Downtown
Booked 42 times today
Embrace the unique and step into the old school at Dean’s Steak & Seafood. Adapted into a historic 19th-century schoolhouse, this classic steakhouse and bar offers an elevated menu of prime steaks, A5 Japanese and Texas wagyu, and top-quality seafood. Simply put, this one-of-a-kind steakhouse is unlike anything else in the city.If you're looking for an elevated bar experience, visit The Study at Dean's. This intimate speakeasy bar is a cocktail aficionado’s haven, ideal for those who appreciate higher touch ingredients, presentation, and ambiance. Linger over high-end cocktails and small bites in a charming atmosphere with raised banquettes, brass details, and a dedicated outdoor patio shaded under century-old live oak trees - this is the educated choice for a place to connect and unwind.
A photo of Savor The Culinary Institute of America restaurant
4.9
Exceptional(1408)
Price: Expensive
• Contemporary American • Downtown
Booked 3 times today
Located on the campus of The Culinary Institute of America, San Antonio, and nestled in the Pearl, Savor highlights the talents of our CIA students under the supervision of the college’s world class faculty. Experience a meal inspired by ingredients and techniques from around the world. Our dining room and patio are open and reservations are strongly encouraged. Curbside takeout is also available. All guests are required to wear a mask while indoors—regardless of their vaccination status—except when seated in a dining environment. Thank you for helping to keep our CIA campus community safe!
A photo of Perry's Steakhouse & Grille - San Antonio restaurant
4.8
Exceptional(9336)
Price: Expensive
• Steakhouse • La Cantera
Booked 85 times today
Located in La Cantera, Perry’s is a great place to spend an evening in The River City. Our popular Bar 79® presents floor-to-ceiling windows with an optional open-air lounge experience and expansive views overlooking local shops. Plus, the spacious, open design gives you the chance to catch glimpses of the chef as he crafts your favorite dishes — adding to the fresh, familiar atmosphere.
A photo of Haywire - La Cantera restaurant
4.4
Awesome(57)
Price: Expensive
• American • La Cantera
Booked 108 times today
Haywire is a Texas-inspired restaurant known for larger-than-life dining experiences, an award-winning wine cellar and extensive list of highly allocated whiskeys. Haywire delivers a true Texas experience through an innovative farm-to-fork menu complete with vendor partners representing every corner of the state.
A photo of Chart House Restaurant - Tower of the Americas restaurant
4.5
Awesome(16561)
Price: Moderate
• Seafood • Downtown
Booked 167 times today
Chart House is a fine dining restaurant serving seafood & steak and famous for their spectacular views. For more than 50 years, Chart House has redefined the ideal dining experience. With 27 waterfront and showcase locations ranging from the historic to the unforgettable, Chart House restaurants specialize in dazzling views, unique cuisine and exceptional service. From fresh fish specialties to slow-roasted prime rib, the renowned chefs of Chart House have tailored a menu that adds a unique touch to local flavors. And the Chart House happy hour is a guest favorite, where guest favor our signature cocktails and delicious bites you are sure to enjoy. Our original Hot Chocolate Lava Cake is the perfect end to a memorable dining experience at Chart House. Chart House offers the ideal setting for your next event. We would be happy to assist you with all the details of your special occasion.
A photo of Brasserie Mon Chou Chou restaurant
4.8
Exceptional(3388)
Price: Moderate
• French • Downtown
Booked 69 times today
Brasserie Mon Chou Chou is a vibrant place, bustling with energy and celebrated food prepared in a French style, with free-flowing drinks and people connecting over the every day and the special. We feature quintessential French comfort food that showcases simple, earthy, flavorful dishes from regions throughout France. Brasserie Mon Chou Chou is located in the Pearl district near the entrance of the hotel Emma at 312 Pearl Parkway Building 2, Suite 2104, in the space formerly occupied by The Culinary Institute of America's Nao. "Mon Chou Chou" is an affectionate French nickname given to a person who is special to you. Usually a person of unmatched care, love, and beauty who makes your world "go round".
A photo of Chama Gaucha - San Antonio restaurant
4.9
Exceptional(6501)
Price: Very Expensive
• Brazilian Steakhouse • Stone Oak
Booked 164 times today
Welcome to Chama Gaucha Brazilian Steakhouse – where the ultimate dining experience awaits! Indulge your senses in a culinary journey like no other, as we offer an authentic taste of Brazil with our prime cut meats and unwavering commitment to superior service. Our expert gauchos skillfully carve an array of succulent, mouthwatering cuts right at your table, allowing you to savor the flavors and tenderness with every bite.But it's not just the extraordinary dishes that set us apart; it's the service that elevates your visit to unforgettable heights. Our attentive and knowledgeable staff are committed to ensuring that every moment of your dining experience is nothing short of exceptional.Whether you're celebrating a special occasion, enjoying a night out with friends, or simply seeking an extraordinary meal, Chama Gaucha promises to elevate your dining experience to new heights.
A photo of Isidore restaurant
4.6
Exceptional(86)
Price: Very Expensive
• Farm-to-table • Downtown
Booked 22 times today
Join us for dinner, as we showcase the bounty of Texas. This ever-changing menu will highlight the best of the season and work closely to reflect the treasures within the market. Isidore will have a robust wine list and intimate décor, making it the perfect space to celebrate.
A photo of Bohanan's Prime Steaks and Seafood restaurant
4.8
Exceptional(8261)
Price: Very Expensive
• Steakhouse • Downtown
Booked 53 times today
Bohanan’s fame is founded on sublimely tender prime beef grilled over fragrant mesquite wood. Enjoy extraordinarily delicious Akaushi beef, Chef/Owner Mark Bohanan’s large custom cuts of prime aged corn-fed beef, succulent seafood flown in fresh daily, and spectacular table-side desserts flambé. Imbibe a classic cocktail at the first-floor Bar at Bohanan’s, then join us upstairs for the best steak you’ve ever eaten. Located in a historic building in downtown San Antonio about a block from the River Walk. AAA Four Diamond rating and Wine Spectator’s Best of Award of Excellence.
A photo of Mezquite restaurant
4.5
Awesome(194)
Price: Moderate
• Northern Mexican • Downtown
Booked 47 times today
THE FLAVORS OF SONORACelebrating the food pathways of the Sonoran region, Mezquite offers grilled meats, flour tortillas and delicious cocktails. This vibrant space is perfect for gathering with friends and reveling in the end of a work week. Open for lunch and dinner, you won’t want to leave.

See what locals rave about

From verified diners like you
From verified diners like you
  • Privacy policy
  • Terms of Use
  • Cookies and Interest-Based Ads
  • Cookie Preferences
Copyright © 2024 OpenTable Australia Level 22, 357 Collins Street, Melbourne, Victoria - All rights reserved.
OpenTable is part of Booking Holdings, the world leader in online travel and related services.
Booking Logo
Priceline Logo
KAYAK Logo
Agoda Logo
OpenTable Logo