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Best Comfort Food Restaurants in Medical Center

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15 restaurants available nearby

A photo of Whiskey Cake - San Antonio restaurant
4.7
Exceptional(4234)
Price: Moderate
• Farm-to-table • La Cantera
Booked 164 times today
Whiskey Cake in San Antonio is a comfort food haven. The restaurant's approachable menu features New American comfort food, sourcing as much as possible locally. Signature dishes include slow-cooked meats and the famous whiskey cake for dessert. The farm-to-fork mission is evident in the fresh, high quality ingredients. Reviewers consistently mention the 'comfort food' options, 'fresh and light yet feel like comfort foods', and 'great food always consistent with awesome flavors'. The restaurant's inviting atmosphere, great service, and unique menu add to the comfort food experience.
A photo of Best Quality Daughter restaurant
4.8
Exceptional(544)
Price: Moderate
• Unspecified • Downtown
Booked 119 times today
Best Quality Daughter houses a vibrant, chic décor and new, unique Asian-American menu. In 2018, chef Jennifer Hwa Dobbertin, wanting to address the sparsity of Asian-American female chefs in South Texas, developed a new concept through a series of pop-up dinners called Best Quality Daughter with fellow chef Anne Ng and artist Jennifer Ling Datchuk. Today Best Quality Daughter is located in the historic Mueller House at the Pearl Brewery. Curated by chef Jennifer Hwa Dobbertin, Best Quality Daughter's menu takes inspiration from her travels and the comfort food of her youth as a second-generation Chinese-American.
A photo of Ambler - Texas Kitchen + Cocktails restaurant
4.2
Awesome(571)
Price: Moderate
• Contemporary American • Downtown
Booked 13 times today
Ambler - Texas Kitchen + Cocktails is a comfort food haven with its 'fantastic service' and 'superb meals' praised by reviewers. The 'great food', 'great atmosphere' and 'friendly staff' make it a 'comfortable' spot. The menu, inspired by Texas, boasts 'jaw-dropping views' and 'vibrant flavors'. From 'exotic menu' to 'excellent food and cocktails', Ambler is the perfect spot for a comforting meal.
A photo of Brasserie Mon Chou Chou restaurant
4.8
Exceptional(3437)
Price: Moderate
• French • Downtown
Booked 92 times today
Brasserie Mon Chou Chou is a vibrant place, bustling with energy and celebrated food prepared in a French style, with free-flowing drinks and people connecting over the every day and the special. We feature quintessential French comfort food that showcases simple, earthy, flavorful dishes from regions throughout France. Brasserie Mon Chou Chou is located in the Pearl district near the entrance of the hotel Emma at 312 Pearl Parkway Building 2, Suite 2104, in the space formerly occupied by The Culinary Institute of America's Nao. "Mon Chou Chou" is an affectionate French nickname given to a person who is special to you. Usually a person of unmatched care, love, and beauty who makes your world "go round".
A photo of Carriqui restaurant
4.8
Exceptional(731)
Price: Expensive
• Unspecified • Downtown
Booked 105 times today
COOKING WITH FIRE, SOUTH TEXAS STYLE Carriqui celebrates the South Texas tradition of drawing flavor from fire. Inspired by the flight path of our namesake bird, our menus feature regional favorites from the Rio Grande Valley, Texas coast, and the Hill Country. Nearly every dish is touched by the glowing embers of our custom-forged pits, smoker, or grill, all fueled by native wood. Along with housemade tortillas, cold margaritas, and warm hospitality, each meal is an opportunity to experience the vibrant food and spirit of our South Texas culture.
A photo of Tokyo Cowboy restaurant
4.6
Exceptional(248)
Price: Expensive
• Tapas / Small Plates • Downtown
Booked 42 times today
Asian-inspired diner with creative cocktails and a great selection of whisky!
A photo of Joe's Crab Shack - San Antonio restaurant
3.0
Good(24)
Price: Moderate
• Seafood • Downtown
Booked 7 times today
Joe’s Crab Shack offers a variety of favorites from all parts of the sea and shore. From its extensive menu, guests can choose from buckets of seasonal seafood, fried shrimp platters and fish dishes, as well as options from the “mainland” that include steak, sandwiches, and chicken. Guests can indulge in over-sized and creative cocktails, such as the Shark Bite which is playfully garnished with a shark toy. Since its inception, Joe’s popularity has stemmed not only from its menu, but also its retail store. With various pieces of merchandise for purchase, including the ever-popular tie-dye T-shirt with the phrase “Peace, Love and Crabs,” Joe’s has become synonymous with the word “fun.”
A photo of Esquire Tavern restaurant
4.4
Awesome(654)
Price: Expensive
• American • Downtown
Booked 19 times today
Located in the heart of downtown, The Esquire Tavern is the oldest bar on the San Antonio Riverwalk, opened the year, month and day that Prohibition was repealed. Tending bar in the early days was a highly prized and much sought after craft. Bar keeps then created many of their own syrups, mixes and concoctions and used the freshest of juices with the intention of serving the best products. We at the Esquire have taken a serious approach to the old world of bartending and spun it with a modern twist. Combining classic techniques and new world flavors and culinary concepts, our goal is to lead and set San Antonio's emerging cocktail culture on the map.
A photo of Sustenio - Eilan Hotel restaurant
3.0
Good(692)
Price: Moderate
• Southwest • La Cantera
Booked 1 time today
Enjoy the diverse flavors of South Texas at Sustenio! Local fresh produce and proteins brought in daily; with influences from Traditional Mexico, Creole and Southern Comfort foods.
A photo of Bazille – Nordstrom La Cantera restaurant
4.7
Exceptional(100)
Price: Moderate
• Contemporary American • La Cantera
Booked 1 time today
Bold flavors elevate beloved bistro classics in chic and inviting Bazille. Meet up with friends at the bar for internationally sourced wines and handcrafted cocktails. Stay for appetizers, salads, brick-oven pizzas and our tempting housemade desserts.The Bazille is located on level 2 inside Nordstrom at The Shops at La Cantera. Join us for Brunch on weekends.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

See what locals rave about

From verified diners like you
From verified diners like you
  • Alexander
    Las Vegas •1 review
    5.0
    Dined 1 day ago
    Great location,great service ,great food. Definitely will go again.
    More info
    Whiskey Cake - San AntonioPrice: Moderate• Farm-to-table• La Cantera
    4.7
  • Charlotte
    San Antonio •4 reviews
    5.0
    Dined 1 day ago
    First time to this restaurant. It was really very nice and will go back. I went for lunch with friends and enjoyed the menu selections. One person got the Brisket and raved about it. I got one of the bowls they offer and was very pleased with it. It had a wonderful flavor. It was filling and I ended up bringing some home. Server was very welcoming offered suggestions on the drink menu and food menu. This place would be a nice place to go to for a larger crowd as I noticed they had a room with a large table, plus several tables in the upstairs area that could be put together. I recommend Carriqui.
    More info
    CarriquiPrice: Expensive• Unspecified• Downtown
    4.8
  • JulieVIP
    San Antonio •43 reviews
    5.0
    Dined 2 days ago
    We had a great dinner and good service last night. The dining room was a little loud (energetic in OT scale) but we could still talk. Had a nice bottle of wine as well. Our server was attentive and helpful. My colleagues ordered the rotisserie chicken and ate every bit. We split some salads and I had mussels. They were delicious in an unexpected red sauce. Don't miss the baguette service either before or with dinner.
    More info
    Brasserie Mon Chou ChouPrice: Moderate• French• Downtown
    4.8
  • Robert
    San Antonio •6 reviews
    5.0
    Dined 3 days ago
    A best friend and I were seated promptly. This was his first time, my upteenth. We ordered three "smaller" dishes which were quite large: popcorn chicken, garlic noodles, brussel sprouts, each were absolute stellar. The chicken had the most delightful hint of spice. The garlicky noodles were close-your-eyes sublime, the brussel sproats were delicious and, dare I say, juicy! He had a few Thai ales, I was driving. We feasted. It was decadent. We finished with an enormous bowled duck confit which was absolutely mind-blowing. The buttery broth! We caught up, as friends are aught to do. The food made the conversation that much better. Best Quality Daughter is next level. Life is too short for dull food. Go to BQD and really live.
    More info
    Best Quality DaughterPrice: Moderate• Unspecified• Downtown
    4.8
  • BobbyVIP
    Houston •2 reviews
    5.0
    Dined 7 days ago
    Very friendly and attentive staff. Food was good and great presentation. Portions were good size.
    More info
    Ambler - Texas Kitchen + CocktailsPrice: Moderate• Contemporary American• Downtown
    4.2
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