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Best Comfort Food Restaurants in Medical Center

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9 restaurants available nearby

A photo of Whiskey Cake - San Antonio restaurant
1. Whiskey Cake - San Antonio
4.8
Exceptional(4193)
Price: Moderate
• Comfort food • La Cantera
Booked 54 times today
Whiskey Cake in La Cantera, San Antonio, is a gem for those seeking authentic American cuisine with a modern twist. Renowned for its farm-to-table approach, this award-winning restaurant excels in serving up New American comfort food that's as inventive as it is delightful. Patrons rave about the "delicious farm bird and fried green tomatoes," and the signature whiskey cake, described as "always my favorite!" The diverse, locally-sourced menu, coupled with a vibrant, pre-prohibition bar vibe, makes Whiskey Cake a standout. It's not just a meal; it's an experience where every dish tells a story of culinary excellence and local bounty.
A photo of Ambler - Texas Kitchen + Cocktails restaurant
2. Ambler - Texas Kitchen + Cocktails
4.3
Awesome(544)
Price: Moderate
• Comfort food • Downtown
Booked 12 times today
Ambler - Texas Kitchen + Cocktails, nestled in the heart of Downtown San Antonio, is a haven for Comfort Food lovers seeking authenticity and robust Texas flavors. Situated on the scenic Riverwalk, Ambler celebrates the state's rich cattle ranching history with a menu that's as bold and inviting as Texas itself. From the "flavorful and cooked to perfection" Fried Chicken Dinner and Salmon to the "best pork chop I’ve ever had," guests consistently praise the quality and heartiness of the meals. Coupled with its vibrant environment and exceptional service, Ambler ensures a memorable dining experience. As one diner put it, "The steak is amazing! The service is first class," making it a must-visit for anyone craving genuine Texas Comfort Food.
A photo of Esquire Tavern restaurant
3. Esquire Tavern
4.4
Awesome(645)
Price: Expensive
• Comfort food • Downtown
Booked 21 times today
Nestled in the historic heart of downtown San Antonio, The Esquire Tavern offers a culinary retreat with its exceptional Comfort Food. Known as the oldest bar on the San Antonio Riverwalk, this tavern not only boasts a rich history but also a mastery in creating soul-satisfying dishes. Guests rave about the "delicious" chicken fried steak and the "outstanding" Esquire cheeseburger, highlighting both as must-try items. The tavern's commitment to quality is evident, with reviews praising the "perfectly seasoned" Picadillo Fries and the "so so good" Chicken Tortilla Soup. The atmosphere, described as "moody" and "relaxing," complements the comfort food menu, making The Esquire Tavern a beloved spot for both locals and visitors seeking a taste of San Antonio's culinary heritage.
A photo of Sustenio - Eilan Hotel restaurant
4. Sustenio - Eilan Hotel
4.2
Awesome(690)
Price: Moderate
• Comfort food • La Cantera
Booked 1 time today
Enjoy the diverse flavors of South Texas at Sustenio! Local fresh produce and proteins brought in daily; with influences from Traditional Mexico, Creole and Southern Comfort foods.
A photo of Joe's Crab Shack - San Antonio restaurant
5. Joe's Crab Shack - San Antonio
3.7
Very Good(18)
Price: Moderate
• Comfort food • Downtown
Booked 5 times today
Joe’s Crab Shack offers a variety of favorites from all parts of the sea and shore. From its extensive menu, guests can choose from buckets of seasonal seafood, fried shrimp platters and fish dishes, as well as options from the “mainland” that include steak, sandwiches, and chicken. Guests can indulge in over-sized and creative cocktails, such as the Shark Bite which is playfully garnished with a shark toy. Since its inception, Joe’s popularity has stemmed not only from its menu, but also its retail store. With various pieces of merchandise for purchase, including the ever-popular tie-dye T-shirt with the phrase “Peace, Love and Crabs,” Joe’s has become synonymous with the word “fun.”
A photo of Bazille – Nordstrom La Cantera restaurant
6. Bazille – Nordstrom La Cantera
5.0
Exceptional(99)
Price: Moderate
• Comfort food • La Cantera
Booked 5 times today
Bold flavors elevate beloved bistro classics in chic and inviting Bazille. Meet up with friends at the bar for internationally sourced wines and handcrafted cocktails. Stay for appetizers, salads, brick-oven pizzas and our tempting housemade desserts.The Bazille is located on level 2 inside Nordstrom at The Shops at La Cantera. Join us for Brunch on weekends.
A photo of Sugar Factory - San Antonio restaurant
7. Sugar Factory - San Antonio
3.7
Very Good(496)
Price: Expensive
• Comfort food • Downtown
Booked 9 times today
Sugar Factory in Downtown San Antonio is a dessert lover's paradise, celebrated for its remarkable dedication to the craft of sweet treats. Known for its "over-the-top dishes, sweets and treats," this restaurant has become a must-visit destination on the River Walk for anyone with a sweet tooth. Guests rave about the "rainbow brite insane milkshake" and the "King Kong Sunday," highlighting the creativity and extravagance of their dessert menu. The vibrant atmosphere and friendly staff add to the delightful dining experience, making every visit memorable. One visitor exclaimed, "The desserts were top notch," perfectly capturing the essence of what makes Sugar Factory a standout in dessert cuisine. Whether celebrating a special occasion or simply indulging in a dessert feast, Sugar Factory delivers an exceptional and unforgettable experience.
A photo of Cover 3 - San Antonio restaurant
8. Cover 3 - San Antonio
4.4
Awesome(51)
Price: Moderate
• Comfort food • North Central
Booked 5 times today
Cover 3 in North Central San Antonio is a comfort food haven, celebrated for its "best Mac N Cheese" and "best Wings," making it a standout in the local dining scene. Patrons rave about the authenticity and flavor of each dish, including the "chicken sliders with white gravy" and the "French onion truffle burger" which are described as "delicious." The restaurant’s commitment to quality is evident, as guests note, "Every meal we've had there, we've wanted to personally thank the chef." The ambiance, combined with an acclaimed Bloody Mary & Bubbles Bar, ensures a delightful dining experience. Their "Buffalo chicken salad" and "peach cake" come highly recommended, capturing the essence of true comfort food with a unique twist. Cover 3 is more than just a restaurant; it's a culinary experience praised for its "great food and service," making it a must-visit for comfort food lovers.
A photo of Maggiano's - San Antonio restaurant
9. Maggiano's - San Antonio
4.8
Exceptional(4008)
Price: Moderate
• Comfort food • Northwest
Booked 69 times today
Maggiano's Little Italy, nestled in the heart of Northwest San Antonio, near iconic locations like The Alamo and the Riverwalk, is a haven for those craving authentic American cuisine with an Italian twist. Known for its "huge portions" and "absolutely delicious" food, Maggiano's has become a beloved spot for both locals and visitors. Diners rave about the "friendly atmosphere" and "excellent service," noting that the restaurant is perfect for everything from "date night" to "large gatherings." Reviews consistently praise dishes like the "FAMOUS RIGATONI 'D'" and the "CHICKEN PARMESAN," highlighting the "rich" flavors and "perfect" preparation. Whether it's a celebration or a casual meal out, Maggiano's promises an exceptional dining experience with "great food and service" in an "upscale" setting, making it a must-visit destination in San Antonio.
‘About the restaurant’ descriptions have been generated using an artificial intelligence model comprised of OpenTable proprietary data that has not been independently verified by OpenTable. The content is presented as-is, for informational purposes only.

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